曾黎燕，博士，仲恺农业工程学院特聘副教授。
个人简介
从事功能性小分子化合物的设计、合成、改性及在农业领域的应用挖掘，发表SCI论文25篇，其中一作或通讯17篇，专利4项，国家级课题2项，研究领域包括：
1）天然来源的抗菌抗炎药物及兽用添加剂研发；
2）可食用保鲜剂及保鲜膜的研发；
3）功能性小分子的设计、合成及其抗炎抗菌活性研究。
目前为止，在Food Chem., Eur. J. Med. Chem., Antioxidant, ACS Comb. Sci.，Eur. J. Med. Chem.，Expert. Opin. Inv. Drug.，Inflammation, Org. Biolog. Chem..等化学和医药学国际型期刊以一作或通讯作者发表SCI论文20余篇。主持国家级项目2项，授权专利数项，指导省级大学生创新创业训练计划项目4项，优秀班主任，农村科技特派员。
教育背景
2003.9~2007.7 南京理工大学 制药工程 学士
2007.9~2012.7 南京理工大学 （保送硕博连读）
应用化学-化学工程与技术 博士
工作经历
2012.12: 美国加州，The Scripps Research Institute，Baran教授组，Research Assistant
2014.1-2015.6 : 美国加州BroadPharm公司，承担药物研发项目
2015.12-2017.12: 南方医科大学药学院，病毒免疫药物药理学博士后，承担抗流感病毒药物研发的课题
2018.6-2019.6 ：南方医科大学附属医院药剂科
2019.6- : 仲恺农业工程学院 化学化工学院 特聘副教授
主要学术成果
(1) H.U. Javed, N.D. Kularathnage, J. Du, R. Liu, Z. Yang, S. Zhong, J. Zhou, X. Shu*, L.-Y. Zeng*. A novel synthesized vanillin-based deep eutectic agent (V-DEA) mitigating postharvest fungal decay and improve shelf life and quality of cherry tomatoes. Food Chem. 2024,453, 139612.
(2) H.U. Javed, R. Liu, C. Li, S. Zhong, J. Lai, M. Hasan, X. Shu*, L.Y. Zeng*. Preparation of Vanillin-Taurine Antioxidant Compound, Characterization, and Evaluation for Improving the Post-Harvest Quality of Litchi. Antioxidants, 2023, 12, 618.
(3) L. Y. Zeng, Yang Liu, Jiakun Han, Jinhong Chen, S. Liu*, and Baomin Xi*. O-Methylation of carboxylic acids with streptozotocin. Org. Biomol. Chem., 2022, 20, 5230-5233.
(4) L.Y. Zeng, Fubiao Yang, Kaixuan Chen, Yunong Zeng, Zhenzhou Jiang, Shuwen Liu*, Baomin Xi*. The one-pot synthesis of butyl-1H-indol-3-alkylcarboxylic acid derivatives in ionic liquid as potent dual-acting agent for management of BPH. Eur. J. Med. Chem., 2020, 205, 112616.
(5) L. Y. Zeng, Y. Wang, N. Li, Y. Wang*, P. Chen*. "Protective effect of a novel (2S, 3R, 4S)-chromene-3-carboxamide derivative, Z20 against sepsis-induced organ injury. Inflammation. 2020, 43, 1222-1232.
(6) L. Y. Zeng, B. Xi, K. Huang, J. Bi, L. Wei, C. Cai*, S. Liu*. Diastereoselective synthesis of 3,4-dihydropyran-3-carboxamides with in vitro anti-inflammatory activity, ACS Comb. Sci. 2019, 21(10): 656-665.
(7) L. Y. Zeng, J. Yang, S. Liu*. Investigational hemagglutinin-targeted influenza virus inhibitors. Expert. Opin. Inv. Drug. 2017, 26（1）: 63-73.
(8) L. Y. Zeng, T. Liu, Y. Yang, J. Yang, C. Cai, S. Liu*. “On-water” facile synthesis of novel pyrazolo[3,4-b]pyridinones processing anti-influenza virus activity. ACS Comb. Sci., 2017, 19 (7): 437-446.
(9) Z. Liu, L. Y. Zeng, C. Li, F. Yang, F. Qiu, S. Liu, B. Xi*. “On-water” synthesis of quinazolinones and dihydroquinazolinones starting from o-bromobenzonitrile. Molecule, 2018. 23(9):2325-2337.
(10) L. Y. Zeng, C. Cai. Iodine Catalyzed One-Pot Multicomponent Synthesis of a Library of Compounds Containing Tetrazolo[1,5-a]pyrimidine Core. J. Comb. Chem., 2010, 12, 35-40. L. Y. Zeng, C. Cai. A Domino Synthesis of Benzoquinolinamide in the Presence of Iodine. Org. Biomol. Chem., 2010, 8（21）, 4903-4905. L. Y. Zeng, W. B. Yi, C. Cai. Three-component Domino Synthesis of 2-Aryl-quinazoline-4-amines in One-pot Via Activating Sp3 C-H Bond in Non-metal Catalytic Oxidation System. Eur. J. Org. Chem., 2012, （3），559-566.
(11) H.U. Javed, D. Wang, M. Abdullah Hasan, L.Y. Zeng, Y. Lan, Y. Shi, and CQ. Duan. Interrogating Raisin Associated Unsaturated Fatty Acid Derived Volatile Compounds Using HS–SPME with GC–MS. Foods. 2023, 12, 428. (IF 5.561).
(12) P. Chen, Z.Wang, L. Zeng, S. Wang, W. Dong, A. Cai, J. Zhang. Protective Effects of Salecan Against Carbon Tetrachloride-induced Acute Live Injury in Mice. J. Appl. Toxicol., 2012, 32: 796-803.
(13) P. Chen, Z. Wang, L. Zeng, X. Yang, S. Wang, W. Dong, A. Jia, C. Cai, J. Zhang. A Novel Soluble Beta-glucan Salecan Protects Against Acute Alcohol-induced Hepatotoxicity in Mice. Biosci. Biotechnol. Biochem., 2011, 75: 1990-1993.
(14) S. Gong, T. Lan, L. Zeng, H. Luo, X. Yang, N. Li, X. Chen, Z. Liu, R. Li, S. Win, S. Liu, H. Zhou, B. Schnabl, Y. Jiang, N. Kaplowitz, P. Chen. Gut microbiota mediates diurnal variation of acetaminophen induced acute liver injury in mice. J. Hepatol. 2018, 69(1): 51-59.
(15) D. Li, Y. Chen, M. Wan, F. Mei , F. Wang, P. Gu, X. Zhang, R. Wei, Y. Zeng, H. Zheng, B. Chen, Q. Xiong, T. Xue, T. Guan, J. Guo, Y. Tian, L. Zeng, Z. Liu, H. Yuan, L. Yang, H. Liu, L. Dai, Y. Yu, Y. Qiu, P. Wu, S. Win, T. Than, R. Wei, B. Schnabl, N. Kaplowitz, Y. Jiang, Q. Ma, P. Chen. Oral magnesium prevents acetaminophen-induced acute liver injury by modulating microbial metabolism. Cell Host Microbe. 2024, 32(1):48-62.e9
专利：
(16) 曾黎燕，刘叔文，习保民，陈鹏，一种2-胺基-3，4-二氢吡喃-3-甲酰胺类似物及其制备方法和用途，中国，ZL201811029410.3, CN 110878074 B
(17) 曾黎燕，陈鹏，李娜，吡喃并色烯-3-甲酰胺衍生物Z20在制备防治脓毒症器官损伤药物中的应用，中国，ZL201811570767.2, CN 111346088 B
(18) 曾黎燕，Hafiz Umer Javed，舒绪刚，林冰涛. 一种牛磺酸缩香草醛席夫碱及其制备方法与应用. 中国，ZL 202211569695.6, CN 116217449 B
(19) 曾黎燕，杜家秀，舒绪刚，Hafiz Umer Javed，钟斯霞.一种功能性深共晶试剂DEA及其制备方法和应用. 中国，2023116541321
